#1 Rated 5-HTP in 2025𐠒

  • Positive mood & relaxation*
  • Promotes restful sleep*
  • Supports appetite control*
  • 200mg 5-hydroxytryptophan in every serving
  • US-made & third party-tested
Shop NowShop Now

60-day money-back guarantee & free shipping.

Limited Offer - 6 bottles of 5-HTP
Save on Subscriptions
60 Day Guarantee
Formulated by Scientists
Shipped Within 24 Hrs
Clean & Potent Formulations
Batch Tested
Made in the US
Save on Subscriptions
60 Day Guarantee
Formulated by Scientists
Shipped Within 24 Hrs
Clean & Potent Formulations
Batch Tested
Made in the US
Benefits of 5-HTP

How you might benefit from
5-HTP:

As with any supplement, individual results may vary. Consistent use for several weeks is often needed to notice benefits. Everyone is uniqueβ€”here’s how supplementation may look for some:*

2-4 weeks

Supports appetite control.*
Aids weight management efforts.*

4-8 Weeks

Supports positive mood.*
Aids with relaxation.*

8+ Weeks

Promotes restful sleep.*

WHAT TO EXPECT

Main Benefits

Brain

Supports Normal Serotonin Synthesis*

5-HTP is a natural precursor to serotonin, a key neurotransmitter for regulating mood, sleep, and appetite.

Better Sleep

Promotes Restful Sleep*

By supporting serotonin’s role in the sleep-wake cycle, 5-HTP may contribute to healthy sleep patterns and a restorative night's rest.*

5-HTP
Anti-Aging

Supports a Balanced Mood*

Regular supplementation may help foster emotional equilibrium, as serotonin is associated with positive mood and well-being.*

Digestive

Helps Manage Appetite*

5-HTP’s influence on serotonin pathways may support healthy appetite regulation, contributing to reduced cravings and better control.*

Ingredients derived from the purest origins

We give you a breakdown of natural ingredients backed by science, meticulously sourced and expertly crafted to deliver unparalleled results.

Griffonia Simplicifolia

5-HTP

Our 5-HTP is derived from the seeds of the African shrub Griffonia simplicifolia, a natural source of 5-HTP. Each serving provides 200 mg per day and is rigorously third-party tested for purity and potency.*

Source

Dose

Final Location of Manufacturing

Griffonia simplicifolia (seed)

200 mg

Utah, United States

Ingredient

mg

Nutrition fact/description here.

Ingredient

mg

Nutrition fact/description here.

Ingredient

mg

Nutrition fact/description here.

Ingredient

mg

Nutrition fact/description here.

Ingredient

mg

Nutrition fact/description here.

Ingredient

mg

Nutrition fact/description here.

Ingredient

1000 mg

We include methylated folate as 5-MTHF, the active form of folic acid. It bypasses common gene variations that make the folic acid to folate conversion more difficult for up to β…“ of people.*

Nutrition Fact

Folate adequacy may also reduce a women’s risk of having a child with neural tube defects.*

One of the top brands on the market

Here's how Meo Nutrition 5-HTP compares to similar products on the market:

5-HTP

MEO

Other brands

Other Brands

200mg per serving

Laboratory-tested

Manufactured in a GMP certified facility

Non-GMO

60 day money-back guarantee

Shop NowShop Now

60-Day Money Back Guarantee

Collage of our Meo Nutrition customers

Join all of our monthly Meo Nutrition subscribers

You’ll save money, time, and effort. It takes consistency and commitment to truly see the biggest results. By joining our community, you'll get access to our:

  • Exclusive Facebook group community
  • E-Books on health and fitness
  • Guides to help you build routines easily
  • Plus so much more!

Web Price

1 Bottle

5-HTP

$29.99

per month

Only $0.99 / day

TOTAL: $29.99 $33.85

25% Savings

Free same-day shipping

ADD TO CART

1 bottle delivered every 30 days

Best Value

6 Bottles

6 Bottles of 5-HTP
6 Bottles of 5-HTP

$24.99

each per month

Only $0.83 / day

TOTAL: $149.94 $272.62

45% Savings

Free same-day shipping

ADD TO CART

6 bottles delivered every 180 days

Most Popular

3 Bottles

3 Bottles of 5-HTP
3 Bottles of 5-HTP

$27.99

each per month

Only $0.93 / day

Total: $83.99 $119.98

30% Savings

Free same-day shipping

Free same-day shipping

ADD TO CART

3 bottles delivered every 90 days

Best Value

45% Off

6 Bottles of 5-HTP
6 Bottles of 5-HTP

6 Months Supply

$24.99

each per month

Free same-day shipping

Subscribe

Total: $149.94 $272.62

Most Popular

3 Bottles of 5-HTP
3 Bottles of 5-HTP

30% off

3 Months Supply

$27.99

each per month

Free same-day shipping

Subscribe

Total: $83.99 $119.98

Web Price

5-HTP
5-HTP
5-HTP

25% off

1 Month Supply

$29.99

per month

Subscribe

Total: $29.99 $33.85

Total: $39.33

Money Back Guarantee

100% Refund Policy

We offer a 100% money-back guarantee within 60 days of receiving any product. Try it out, if you're not happy we'll refund your purchase.

Guaranteed Safe Checkout

Core Values

Plant

Premium Quality

We prioritize uncompromising quality standards in sourcing and manufacturing, ensuring every product surpasses expectations.

Customer Service

Customer-Centric

We are committed to delivering exceptional service and support, prioritizing the needs and satisfaction of our customers at every touchpoint.

Safe

60 Day Guarantee

If you are not satisfied with our product or service, we provide a 60-day, no-questions-asked guarantee. Simply return the product for a full refund.

Trusted By Thousands of Customers and Nutritionists Alike

Older woman in car5-HTP

"Quick delivery & great service."

I have ordered my supplements from Meo Nutrition for years now. I love their fast shipping, great service, and good guarantees. Love the company and their products.

- Karen

Woman smiling5-HTP

"This has everything you could ask for."

Meo Nutrition has become my favorite brand for all my supplement needs. Its rare to see a brand with their level of commitment to high-quality ingredients, and I also appreciate the transparency in their labeling. Never had a problem with their delivery times, and each bottle is packaged securely.

- Stephanie

Woman smiling5-HTP

"The new standard."

I was hesitant to try a new supplement brand, but Meo Nutrition exceeded all my expectations. From the effectiveness of their products to the excellent customer service, everything has been fantastic. The detailed info and usage instructions make it easy to integrate their supplements into my daily routine.

- Julie

Frequently Asked Questions

Got Questions? We've Got Answers

100% Satisfaction Guarantee

We'll refund your money if Meo Nutrition 5-HTP isn't for you!

Order now with confidence! If for any reason you don't think Meo Nutrition 5-HTP is for you, we offer a 60 day money-back guarantee. So if you don't love it, you can get your money back. No questions asked!

Buy NowBuy Now

Customer Reviews

4.7
Rated 4.7 out of 5 stars
Based on 41 reviews
Total 5 star reviews: 29 Total 4 star reviews: 10 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 0
98%would recommend these products
41 reviews
  • Lorraine
    Flag of United States
    Verified Buyer
    Rated 5 out of 5 stars
    3 weeks ago
    Reviewing
    5-HTP
    Had to go off of Zoloft and this is even better

    After having a horrible reaction to Zoloft (cystic acne everywhere!) while being on it for only one month, I had to find something quickly to help me while I was going off of it. I started on Meo Nutrition 5-HTP Plus the very day I stopped my daily 50mg of Zoloft, and I am literally happy to say that I have been stable and have not had one symptom of depression, anxiety or panic attacks. I have been on the 5-HTP Plus (twice a day) for over two weeks and am upbeat, energized, sleeping well and feeling like my old self again. Since I am dealing with peri-menopause, I also (one week later) started taking a supplement "DrFormulas Menopause Supplements for Relief, Support and Weight Loss" in addition for hot flashes and night sweats, which also might be helping my mood, but the 5-HTP, in my opinion, is the main reason I am doing so well mentally and emotionally. I will not be going back on any prescription mood stabilizer, and can't recommend this supplement enough. Be certain to follow directions and take it with food.

    Age Range Over 65
    Gender Female
    My Results Better Mood, Reduced Stress
    ResultsRated 5.0 on a scale of 1 to 5
    Improved HealthRated 5.0 on a scale of 1 to 5
    Overall SatisfactionRated 5.0 on a scale of 1 to 5
  • Chen
    Flag of United States
    Verified Buyer
    Rated 4 out of 5 stars
    3 weeks ago
    Reviewing
    5-HTP
    These work

    After struggling with serotonin uptake levels for years and suffering with depression and fatigue, as a result, I was happy to find a more natural product that actually works. I will not stay 5HPT combats my symptoms alone, but I will say they take the edge off and allow me to avoid taking pharmaceutical prescriptions. Knowing my body and being aware of how my body is handling the stresses in my life (that I can and can not control) helps the effectiveness of this product. This product is worth trying to help easy symptoms. Depression is a misunderstood and overly prescribed medical condition... it is an easy diagnosis for Dr's rather then finding the root cause of symptoms.

    Age Range 25-34
    Gender Female
    My Results Better Mood
    ResultsRated 5.0 on a scale of 1 to 5
    Improved HealthRated 4.0 on a scale of 1 to 5
    Overall SatisfactionRated 5.0 on a scale of 1 to 5
  • Janice
    Flag of United States
    Verified Buyer
    Rated 5 out of 5 stars
    1 month ago
    Reviewing
    5-HTP
    Great product

    I wanted to review this product because I believe it’s really helping me. I didn’t notice any difference at first but the longer I took it, I did start to notice my mood has been lighter and I’m not in a horrible mood 24/7. It’s not a miracle cure for my low moods but it does really take the edge off and my quality of life as been getting better and better. I recommend using this in combination with exercise :). I do not take 200 mg everyday like the bottle describes because I was getting really bad headaches and felt lethargic. That is too much! I take this twice a week, maybe three. I am only giving this four stars because it makes me clench my jaw in my sleep the day I take it and I get a mild headache.

    Age Range 25-34
    Gender Female
    My Results Better Mood
    ResultsRated 5.0 on a scale of 1 to 5
    Improved HealthRated 5.0 on a scale of 1 to 5
    Overall SatisfactionRated 4.0 on a scale of 1 to 5
  • Serenity
    Flag of United States
    Verified Buyer
    Rated 4 out of 5 stars
    1 month ago
    Reviewing
    5-HTP
    Buy. These. !!!

    I'm on day 6 of taking these. I don't know if it's a placebo affect or what, but they are amazing!!! I was a little hesitant with reviews of some people's stomachs being upset. I have a pretty sensitive stomach and no gall bladder so I thought for sure id have issues. But I haven't had any side effects at all. I take them in the morning and they don't make me tired but they do make me ready for bed at night! Usually I lay awake for hours but I've been going to bed around 10 with no issues. I noticed a difference after just two days of taking them. I'm less depressed, more motivated, and I've been getting so much more done. I haven't been nearly as irritabile as usual. The capsules are a bit large, but they have no aftertaste which is nice. I'm going to update this review once I run out and let you know how it's going. If it stays as it is, I'll be buying these for life!!

    Age Range 35-44
    Gender Female
    My Results Better Mood, Weight Loss
    ResultsRated 4.0 on a scale of 1 to 5
    Improved HealthRated 5.0 on a scale of 1 to 5
    Overall SatisfactionRated 4.0 on a scale of 1 to 5
  • Daniel
    Flag of United States
    Verified Buyer
    Rated 4 out of 5 stars
    1 month ago
    Reviewing
    5-HTP
    It does work but it also gives extreme vivid dreams

    I have been taking this product for maybe a month and let me tell you never in my life have I had the dreams I have with these. Insane and to be honest scary a little bit. I had to stop them for a while because the nightmare ( ironically it was causing anxiety on that aspect lol)

    Age Range 25-34
    Gender Male
    My Results Better Sleep
    ResultsRated 4.0 on a scale of 1 to 5
    Improved HealthRated 5.0 on a scale of 1 to 5
    Overall SatisfactionRated 5.0 on a scale of 1 to 5

Meet the Medical Experts Advocating for Our Supplements

At Meo, we collaborate with numerous outstanding and insightful individuals. This includes esteemed scientists, nutritionists, and medical doctors. Their invaluable expertise plays a pivotal role in steering our product innovation and growing our company.

Dr. Brems, PhD

Dr. Brems, PhD

Medical Doctor 

Dr. Zaky, MD

Dr. Zaky, MD

Medical Doctor

Dr. Sila Bal

Dr. Sila Bal

Senior Nutrition Scientist

Dr Abraham

Dr. Abraham, MD

Medical Doctor

HealthPlus
Medical
Biopharm
Thunder

𐠒According to supplement-review.co.

References:

  • Cangiano C, Laviano A, Del Ben M, Preziosa I, Angelico F, Cascino A, Rossi-Fanelli F. Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients. Int J Obes Relat Metab Disord. 1998 Jul;22(7):648-54. doi: 10.1038/sj.ijo.0800642. PMID: 9705024.
  • Cangiano C, Ceci F, Cascino A, Del Ben M, Laviano A, Muscaritoli M, Antonucci F, Rossi-Fanelli F. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr. 1992 Nov;56(5):863-7. doi: 10.1093/ajcn/56.5.863. PMID: 1384305.
  • Ceci F, Cangiano C, Cairella M, Cascino A, Del Ben M, Muscaritoli M, Sibilia L, Rossi Fanelli F. The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. J Neural Transm. 1989;76(2):109-17. doi: 10.1007/BF01578751. PMID: 2468734.
  • Jangid P, Malik P, Singh P, Sharma M, Gulia AK. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian J Psychiatr. 2013 Feb;6(1):29-34. doi: 10.1016/j.ajp.2012.05.011. Epub 2012 Jul 12. PMID: 23380314.
  • Meloni M, Puligheddu M, Carta M, Cannas A, Figorilli M, Defazio G. Efficacy and safety of 5-hydroxytryptophan on depression and apathy in Parkinson's disease: a preliminary finding. Eur J Neurol. 2020 May;27(5):779-786. doi: 10.1111/ene.14179. Epub 2020 Mar 13. PMID: 32067288.
  • Bruni O, Ferri R, Miano S, Verrillo E. L -5-Hydroxytryptophan treatment of sleep terrors in children. Eur J Pediatr. 2004 Jul;163(7):402-7. doi: 10.1007/s00431-004-1444-7. Epub 2004 May 14. PMID: 15146330.