We Reviewed the Top 20 Brands to Find the Best Quality Berberine in 2024
Discover the Top-Ranked Berberine Supplements for 2024
In recent months, we've been inundated with requests to review berberine, a supplement that has rapidly gained popularity online for its impressive effects on weight loss, cholesterol, and blood sugar levels. Responding to this overwhelming interest, we dedicated the past few weeks to thorough research and testing. The result is this comprehensive guide, showcasing our top 5 berberine supplements available in the U.S. for 2024.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Berberine Supplement review article.
What is Berberine?
Berberine is a natural botanical that, just last year, made a resurgence in the natural health scene.
Cultivated from flowering plants like barberry, goldenseal, and Oregon grape, berberine has been used for centuries to treat digestive issues, infections, and inflammation. But the latest research is showing that it can do a whole lot more…
Berberine Can Help With:
- Promoting Healthy Metabolism [2,3]
- Supporting Healthy Blood Sugar Levels [4]
- Promoting Healthy Cholesterol Levels [4,5]
- Natural Remedies [1]
What To Look For In A Berberine Supplement
High Dosage of Pure Berberine
You want to look for at least 1,000 mg of berberine per serving. Be careful to make sure that the dosage is actually for berberine and not for added ingredients, as some companies will dilute their product with other cheaper ingredients.
Made in the USA and Third Party Tested
Make sure the product you select is actually made in the USA, where we have strict manufacturing quality standards. In addition, you want a supplement that is third-party tested, by an independent laboratory. This will help ensure high quality and safety.
60 Day Guarantee
Try to choose a berberine supplement that offers a 100% money-back guarantee. Look for brands that offer at least a 60-day money-back guarantee.
Fair Return Policy
If you are not happy with your product, it should be easy to return your supplement. Avoid brands that make it very difficult to return a product or get a refund.
What To Avoid
Additives and Fillers
Avoid berberine supplements that contain unnecessary additives, fillers, or artificial ingredients. These can dilute the potency of the supplement and may cause adverse reactions in some individuals.
False or Misleading Claims
Beware of any supplements that claim their product treats or cures any specific disease or ailment, or promises miraculous, unrealistic, or misleading results. Always speak to your doctor before starting a new supplement routine.
The Lowest Priced Option
Selecting the cheapest rather than the best quality can potentially do you more harm than good. If brands don’t identify certain ingredients or nutrients and their amounts in each dose, you could end up with an ineffective or potentially harmful supplement.
What We Looked Out For:
Meo Nutrition
Thorne
DR Supplements
Toniiq
Luma Nutrition
Type
Capsule
Capsule
Capsule
Powder
Capsule
Form of berberine
HCI
HCI & Phytosome
HCI
HCI
HCI
Best for
Blood pressure & metabolism
General health
Cholesterol
Natural remedy
General health
Money back guarantee
24/7 customer service
Price point
$$
$$$
$$
$$$
$$
The Top 5 Berberine Supplements in 2024
1. Meo Nutrition Berberine Supplement
Total Ranking
A+
Overall Grade
Pros
- Clean, potent and natural formula.
- Produced in the USA at an FDA licensed facility.
- 60 day, risk free, money back guarantee.
- Recommended by doctors.
- Promotes easier weight loss.
- Subscription and bulk discounts offered.
- Third-party tested/certificate of analysis (COA).
- No artificial ingredients.
- Ships from Texas.
- Over 400,000+ customers.
Cons
- Due to high demand, it may sometimes be sold out.
- Can only be found online.
Conclusion
After reviewing the top 20 berberine supplements, our favorite by far was the Meo Nutrition Berberine Supplement.
Their supplement offers an incredible value featuring a pure and simple formula, which is packed with many healthful benefits including promoting healthy blood sugar and cholesterol levels, as well as a healthy metabolism. [3,4,5]
It contains 1200 mg of berberine and is Vegan, Non-GMO and free of top 9 allergens.
In addition to their focus on science and quality in their products, we were also impressed by the quick shipping and support (we received it the next day), and their customer service team was always quick to reply in the chat box.
In terms of price, this berberine supplement is also incredibly well-priced, coming in at just $0.66 per capsule—or as low as $0.49 per capsule when purchased in bulk.
It has gotten great reviews online, reporting that it's easy to consume, and people have seen good results.
Lastly, they are manufacturing all their supplements in Utah, and they are GMP certified, NSF sports approved, and also UDAF Organic Certified, ensuring quality in every product they sell.
2. Thorne Berberine
Total Ranking
B+
Overall Grade
Pros
- Bioperine from black pepper leads to powerful anti-inflammaging benefits.
- Powerful AMPK pathway activator.
- 3rd-party lab tested.
- 1000 mg of Berberine.
Cons
- Costly at 40% per bottle.
- 1000 mg berberine compared to 1200 mg.
Conclusion
Thorne is a leading company in the supplement industry, known for their quality ingredients, exceptional customer service, and outstanding products. Their berberine supplement is no exception, becoming one of the top-selling berberine products on the market with over 4,000 raving reviews on Amazon.
The berberine supplement from Thorne contains 450 mg of Berberine HCL and 550 mg of Berberine Phytosome complex, making it a potent and diversified formula.
Given their stellar reputation and the clean, potent formula, we are confident in awarding it one of the top spots in our review.
However, Thorne's berberine comes with a high price tag. Thorne also offers a 60-day guarantee, but it's important to note that you will need to cover the return shipping costs if you order directly from their website and not from a marketplace.
Overall, it's an excellent product, and if price is not a primary concern, it's a fantastic choice.
3. DR Supplements Berberine Plus
Total Ranking
B
Overall Grade
Pros
- Sold in popular marketplaces.
- Simple and clean formula.
- Reasonable price.
Cons
- Only 500 mg of berberine per capsule.
- No money-back guarantee.
Conclusion
Berberine Plus is another popular option on the market, making it convenient to order.
One of our concerns was that many people have reported headaches and stomach issues when using this supplement, although this is also the case for some other brands, as it's a side effect of berberine itself.
The reason it earned the third spot on our list is partly because ordering directly from their website was a bit tricky, with limited information on the guarantee and return process.
Their formula contains 1200 mg of Berberine HCl and 10 mg of royal jelly, making it a unique and potent formula.
Overall, it's a great product offered at a reasonable price which is why it has become of the best selling supplements on Amazon.
Reason for the third placement is the lack of 24/7 customer service and not as strong money back guarantee, but besides from this it's a good choice.
4. Toniiq High Strength Berberine
Total Ranking
C
Overall Grade
Pros
- Premium blend made with natural ingredients.
- Houses an exceptional 15:1 Berberine HCL extract.
- Made in the USA.
Cons
- Pricey compared to others in the market.
- No transparent testing information.
Conclusion
Toniiq's High Strength Berberine is another excellent supplement sold in the U.S with 97% purity, and sources its ingredients from the Himalayas.
They clearly have a high priority in clean, high quality ingredients with a 500 mg pure berberine formula.
In addition to this, they have 90 capsules in each box. Although the price tag is slightly higher than others on the market, the price per capsule comes out to be cheaper than many other top brands.
If you have purity as your main focus, want to have smaller dosages in each capsule and a medium price tag then this would be a good choice for you.
5. Luma Nutrition Berberine
Total Ranking
D+
Overall Grade
Pros
- High bioavailability.
- Contains Berberine - Indena Phytosome.
- Gluten-free, Non-GMO & Hypoallergenic.
Cons
- Small number of reviews.
- Only 550 mg capsule.
- Limited guarantees.
Conclusion
Landing the final position on our list, Luma Nutrition's berberine is by no means the least in terms of quality. Among the over 20 brands we evaluated, our standards were rigorous.
Despite its ranking, this product stands out for its merits. It's distinguished by its clean, straightforward formulation, primarily featuring berberine HCl, which offers enhanced bioavailability compared to standard berberine. This means a significant portion of the dose is effectively used by the body.
The high absorption rate of its 1200 mg capsules may outperform even higher-dose products in terms of efficacy.
However, the product does have some downsides: the absence of round-the-clock customer support, and larger capsule size.
Citations
- [1] https://www.naturalmedicinejournal.com/journal/2012-12/clinical-applications-berberine
- [2] https://medlineplus.gov/ency/article/002423.htm
- [3] Ye Yu, Liu Xiufen, Wu Ninghua, Han Yanqi, Wang Jiawen, Yu Yuandong, Chen Qingjie, Efficacy and Safety of Berberine Alone for Several Metabolic Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Frontiers in Pharmacology, 12, 2021, DOI: 10.3389/fphar.2021.653887, ISSN: 1663-9812, https://www.frontiersin.org/article/10.3389/fphar.2021.653887.
- [4] Jacob Schor, Clinical Applications for Berberine, Natural Medicine Journal, March 24, 2014, https://www.naturalmedicinejournal.com/journal/clinical-applications-berberine.
- [5] Kong W, Wei J, Abidi P, et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med. 2004;10(12):1344-1351.
- [6] 26 (12): 3215–3218. https://doi.org/10.2337/diacare.26.12.3215
- [7] https://pubmed.ncbi.nlm.nih.gov/22842630/
- [8] https://pubmed.ncbi.nlm.nih.gov/24174332/
- [9] https://diabetes.diabetesjournals.org/content/55/8/2256.full
What You Will Learn:
Estimated Reading Time: 5 Minutes
- The benefits of a high quality berberine supplement
- What to look for in a berberine supplement
- The top 5 berberine supplements
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*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Supplement Review has with our picks.
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[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Supplement Review has with our picks.